发明授权
- 专利标题： Surface-coated structures and methods
- 专利标题（中）： 表面涂层结构和方法
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申请号： US12899958申请日： 2010-10-07
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公开(公告)号： US08961984B2公开(公告)日： 2015-02-24
- 发明人: Randall T. Irvin , Elisabeth M. Davis , DongYang Li
- 申请人： Randall T. Irvin , Elisabeth M. Davis , DongYang Li
- 申请人地址： CA Alberta
- 专利权人： Arch Biophysics, Inc.
- 当前专利权人： Arch Biophysics, Inc.
- 当前专利权人地址： CA Alberta
- 代理机构： King & Spalding
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/108 ; A61K39/02 ; C07K14/21 ; A61B5/145 ; A61L27/04 ; A61L27/34 ; A61L27/54 ; A61L31/02 ; A61L31/04 ; A61L31/10 ; A61L31/16 ; C12N15/10
摘要：
The present invention relates to a method for covalently attaching a compound to a stainless steel, tin, iron, or titanium substrate, by contacting exposed surface(s) of the substrate with a synthetic pilin peptide containing a disulfide loop derived from the C-terminal receptor binding protein of Type IV P. aeruginosa (T4P) pilin, to bind the pilin peptide to the exposed surface(s), and covalently attaching the compound to the pilin peptide. Also disclosed are a substrate formed by the method and a biosensor device that uses the uses. Also disclosed are methods for improving the corrosion resistance, adhesive force, hardness and electron work function of certain metals.
公开/授权文献
- US20110087321A1 SURFACE-COATED STRUCTURES AND METHODS 公开/授权日：2011-04-14
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