Upstream frequency response measurement and characterization. Signaling is provided between respective communication devices within a communication system. Based upon at least one of these signals, one of the communication devices captures a number of sample sets corresponding thereto at different respective frequencies (e.g., a different respective center frequencies, frequency bands, etc.). Then, spectral analysis is performed with respect to each of the sample sets to generate a respective and corresponding channel response estimate there from. After this number of channel response estimates is determined, they are combined or splice together to generate a full channel response estimate. In implementations including an equalizer, different respective sample sets may correspond to those that have undergone equalization processing and those that have not.