发明授权
US08843356B2 Computer systems and methods for associating genes with traits using cross species data
有权
使用交叉物种数据将基因与性状相关联的计算机系统和方法
- 专利标题： Computer systems and methods for associating genes with traits using cross species data
- 专利标题（中）： 使用交叉物种数据将基因与性状相关联的计算机系统和方法
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申请号： US10540405申请日： 2003-12-24
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公开(公告)号： US08843356B2公开(公告)日： 2014-09-23
- 发明人: Eric E. Schadt , John Lamb
- 申请人： Eric E. Schadt , John Lamb
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理机构： Christensen O'Connor Johnson Kindness PLLC
- 国际申请： PCT/US03/41613 WO 20031224
- 国际公布： WO2004/061616 WO 20040722
- 主分类号： G06G7/58
- IPC分类号： G06G7/58 ; G01N33/48 ; G01N33/50 ; G01N31/00
摘要：
A method for confirming the association of a query QTL or a query gene in the genome of a second species with a clinical trait T exhibited by the second species. A first QTL or a first gene in a first species that is linked to a trait T′ is found. The trait T′ is indicative of trait T. A region of the genome of the first species that comprises the first QTL or the first gene is mapped to a particular region of the genome of the second species. A query QTL or a query gene in the second species that is potentially associated with the trait T is found. The potential association of the query QTL or the query gene with the clinical trait T is confirmed when the query QTL or the query gene is in the particular region of the genome of the second species.
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