A device implements data reception with edge-based partial response decision feedback equalization. In an example embodiment, the device implements a tap weight adapter circuit that sets the tap weights that are used for adjustment of a received data signal. The tap weight adapter circuit sets the tap weights based on previously determined data values and input from an edge analysis of the received data signal using a set of edge samplers. The edge analysis may include adjusting the sampled data signal by the tap weights determined by the tap weight adapter circuit. A clock generation circuit generates an edge clock signal to control the edge sampling performed by the set of edge samplers. The edge clock signal may be generated as a function of the signals of the edge samplers and prior data values determined by the equalizer.