Invention Grant
US08791123B2 Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors
有权
取代的吡唑并[1,5-a]嘧啶化合物作为Trk激酶抑制剂
![Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors](/docs/US/2014-07-29/US08791123B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors
- Patent Title (中): 取代的吡唑并[1,5-a]嘧啶化合物作为Trk激酶抑制剂
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Application No.: US13382858Application Date: 2010-07-09
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Publication No.: US08791123B2Publication Date: 2014-07-29
- Inventor: Shelley Allen , Steven Wade Andrews , Kevin Ronald Condroski , Julia Haas , Lily Huang , Yutong Jiang , Timothy Kercher , Jeongbeob Seo
- Applicant: Shelley Allen , Steven Wade Andrews , Kevin Ronald Condroski , Julia Haas , Lily Huang , Yutong Jiang , Timothy Kercher , Jeongbeob Seo
- Applicant Address: US CO Boulder
- Assignee: Array Biopharma, Inc.
- Current Assignee: Array Biopharma, Inc.
- Current Assignee Address: US CO Boulder
- Agency: Fenwick & West LLP
- International Application: PCT/US2010/041538 WO 20100709
- International Announcement: WO2011/006074 WO 20110113
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D487/00
![Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors](/abs-image/US/2014/07/29/US08791123B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of Formula (I) and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Public/Granted literature
- US20120108568A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS Public/Granted day:2012-05-03
Information query
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