Invention Grant
- Patent Title: 7-phenoxychroman carboxylic acid derivatives
- Patent Title (中): 7-苯氧基苯并二氢吡喃羧酸衍生物
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Application No.: US13141675Application Date: 2009-12-18
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Publication No.: US08785445B2Publication Date: 2014-07-22
- Inventor: Adam Cook , Kevin W. Hunt , Robert Kirk Delisle , Todd Romoff , Christopher T. Clark , Ganghyeok Kim , Christopher P. Corrette , George A. Doherty , Laurence E. Burgess
- Applicant: Adam Cook , Kevin W. Hunt , Robert Kirk Delisle , Todd Romoff , Christopher T. Clark , Ganghyeok Kim , Christopher P. Corrette , George A. Doherty , Laurence E. Burgess
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- Agent Sarah S. Mastous
- International Application: PCT/US2009/068672 WO 20091218
- International Announcement: WO2010/075200 WO 20100701
- Main IPC: C07D405/12
- IPC: C07D405/12 ; A61K31/4433 ; C07D241/20 ; A61K31/497 ; A61K31/501 ; A61P11/06 ; A61P27/14 ; A61P17/00 ; A61P29/00

Abstract:
Compounds of Formula I: (I) in which A, A1, R1, R7a, R7b, R8 and R10 have the meanings given in the specification, are DP2 receptor inhibitors useful in the treatment of useful in the treatment and prevention of immunologic diseases, allergic diseases such as asthma, allergic rhinitis and atopic dermatitis, and other inflammatory diseases mediated by prostaglandin D2 (PGD2). The compounds of Formula I may also be useful in treating diseases or medical conditions involving the Th2 T cell via production of IL-4, IL-5 and/or IL-13.
Public/Granted literature
- US20120101103A1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES Public/Granted day:2012-04-26
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