Invention Grant
- Patent Title: Quinolinone derivatives as PARP and tank inhibitors
- Patent Title (中): 喹啉酮衍生物作为PARP和罐抑制剂
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Application No.: US13617686Application Date: 2012-09-14
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Publication No.: US08778966B2Publication Date: 2014-07-15
- Inventor: Jorge Eduardo Vialard , Patrick René Angibaud , Laurence Anne Mevellec , Christophe Meyer , Eddy Jean Edgard Freyne , Isabelle Noëlle Constance Pilatte , Bruno Roux , Elisabeth Thèrése Jeanne Pasquier , Xavier Marc Bourdrez , Christophe Denis Adelinet , Laurence Françoise Bernadette Marconnet-Decrane , Jacqueline Anne Macritchie , James Edward Stewart Duffy , Andrew Pate Owens , Pierre-Henri Storck , Virginie Sophie Poncelet
- Applicant: Jorge Eduardo Vialard , Patrick René Angibaud , Laurence Anne Mevellec , Christophe Meyer , Eddy Jean Edgard Freyne , Isabelle Noëlle Constance Pilatte , Bruno Roux , Elisabeth Thèrése Jeanne Pasquier , Xavier Marc Bourdrez , Christophe Denis Adelinet , Laurence Françoise Bernadette Marconnet-Decrane , Jacqueline Anne Macritchie , James Edward Stewart Duffy , Andrew Pate Owens , Pierre-Henri Storck , Virginie Sophie Poncelet
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica, NV
- Current Assignee: Janssen Pharmaceutica, NV
- Current Assignee Address: BE
- Priority: EP07103788 20070308
- Main IPC: A61K31/04
- IPC: A61K31/04 ; C07D413/06 ; C07D401/06 ; C07D401/12 ; C07D405/06 ; C07D409/06 ; C07D215/227 ; C07D417/06
Abstract:
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, n, m and X have defined meanings.
Public/Granted literature
- US20130018017A1 QUINOLINONE DERIVATIVES AS PARP AND TANK INHIBITORS Public/Granted day:2013-01-17
Information query
