发明授权
US08742205B2 Dominant negative mutant KRP protein protection of active cyclin-CDK complex inhibition by wild-type KRP
有权
主要负性突变体KRP蛋白保护活性细胞周期蛋白 - CDK复合物抑制野生型KRP
- 专利标题： Dominant negative mutant KRP protein protection of active cyclin-CDK complex inhibition by wild-type KRP
- 专利标题（中）： 主要负性突变体KRP蛋白保护活性细胞周期蛋白 - CDK复合物抑制野生型KRP
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申请号： US11460941申请日： 2006-07-28
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公开(公告)号： US08742205B2公开(公告)日： 2014-06-03
- 发明人: Paul Olivier , Jay DeRocher , James M. Roberts
- 申请人： Paul Olivier , Jay DeRocher , James M. Roberts
- 申请人地址： US WA Seattle
- 专利权人： Targeted Growth, Inc.
- 当前专利权人： Targeted Growth, Inc.
- 当前专利权人地址： US WA Seattle
- 代理机构： Cooley LLP
- 主分类号： A01H1/00
- IPC分类号： A01H1/00 ; A01H5/00 ; C12N15/87 ; C12N15/82 ; C12N5/04 ; C12N5/10 ; C07H21/04
摘要：
Disclosed are mutant CDK inhibitor (CKI) polypeptides having dominant negative antagonist activity against wild-type CKI proteins, as well as related compositions, including nucleic acids and vectors encoding the mutant CKI polypeptides and transformed host cells and transgenic plants comprising such nucleic acids and vectors. Also disclosed are related methods for using the mutant proteins to modulate cell division in cells, particularly plant cells.
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