发明授权
- 专利标题: Method for risk stratification in stable coronary artery disease
- 专利标题(中): 稳定性冠状动脉疾病风险分层方法
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申请号: US12671823申请日: 2008-08-01
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公开(公告)号: US08735079B2公开(公告)日: 2014-05-27
- 发明人: Andreas Bergmann , Joachim Struck , Nils G. Morgenthaler , Jana Papassotiriou , Stefan Blankenberg , Karl Lackner , Hans Rupprecht , Christoph Bickel
- 申请人: Andreas Bergmann , Joachim Struck , Nils G. Morgenthaler , Jana Papassotiriou , Stefan Blankenberg , Karl Lackner , Hans Rupprecht , Christoph Bickel
- 申请人地址: DE Hennigsdorf
- 专利权人: B.R.A.H.M.S GmbH
- 当前专利权人: B.R.A.H.M.S GmbH
- 当前专利权人地址: DE Hennigsdorf
- 代理机构: Heslin Rothenberg Farley & Mesiti P.C.
- 优先权: EP07015271 20070803
- 国际申请: PCT/EP2008/006378 WO 20080801
- 国际公布: WO2009/018979 WO 20090212
- 主分类号: G01N33/53
- IPC分类号: G01N33/53
摘要:
An in vitro method for the risk stratification of patients with stable arteriosclerosis, especially stable coronary artery disease, is disclosed wherein the concentration of procalcitonin is determined in the circulation of such patients using a highly sensitive PCT assay, and wherein within the range of PCT concentrations in the typical normal range of healthy individuals cutoff values are defined which distinguish groups of individual patients with stable arteriosclerosis in accordance with personal cardiac risk, and patients are allotted to one of said risk groups on the basis of their individual PCT concentrations.
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