A method and apparatus for feeding a polyurethane mixture suitable to form a thermally insulating layer inside hollow bodies, such as hollow walls of a refrigerator cabinet, freezer, display counter or insulating panel. A polyurethane mixture resulting from chemically reactive components, supplied by a high-pressure mixing device, is injected into a cavity of a hollow body extending in a horizontal plain. The mixture is injected at a first flow-rate and a first injection speed, to be poured into a first deposition zone farthest from the injection point. Subsequently, the flow-rate and the injection speed of the polyurethane mixture are gradually reduced in a controlled manner, to be poured in successive deposition zones towards the injection point of the polyurethane mixture, along a distribution strip, allowing the injected mixture to spread out throughout the cavity of the hollow body along isometric expansion lines.