Invention Grant
US08697370B2 Biomarker for diagnosis, prediction and/or prognosis of sepsis and uses thereof
失效
用于诊断，预测和/或脓毒症预后的生物标志物及其用途
- Patent Title: Biomarker for diagnosis, prediction and/or prognosis of sepsis and uses thereof
- Patent Title (中): 用于诊断，预测和/或脓毒症预后的生物标志物及其用途
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Application No.: US12990841Application Date: 2009-05-19
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Publication No.: US08697370B2Publication Date: 2014-04-15
- Inventor: Koen Kas , Griet Vanpoucke
- Applicant: Koen Kas , Griet Vanpoucke
- Applicant Address: BE Zwijnaarde
- Assignee: Pronota N.V.
- Current Assignee: Pronota N.V.
- Current Assignee Address: BE Zwijnaarde
- Agency: Knobbe, Martens, Olson & Bear LLP
- Priority: EP08156837 20080523
- International Application: PCT/EP2009/056094 WO 20090519
- International Announcement: WO2009/141359 WO 20091126
- Main IPC: G01N31/00
- IPC: G01N31/00 ; G01N33/53
Abstract:
Methods for the diagnosis, prognosis and prediction of sepsis in a subject using the expression levels of the biomarkers Triggering Receptor Expressed on Myeloid cells-1 (TREM-1) and TREM-like receptor transcript-1 (TLT1) as an indication of the condition of the patient, alone or in combination with further sepsis markers are disclosed. If the levels of the biomarkers indicate the presence of sepsis, the patient is treated for sepsis with an antibiotic and/or fluid resuscitation treatment.
Public/Granted literature
- US20110059858A1 NEW BIOMARKER FOR DIAGNOSIS, PREDICTION AND/OR PROGNOSIS OF SEPSIS AND USES THEREOF Public/Granted day:2011-03-10
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