A data processing system comprises data processing circuitry, a cache memory, and memory access circuitry. The memory access circuitry is operative to assign a memory address region to be allocated in the cache memory with a predefined initialization value. Subsequently, a portion of the cache memory is allocated to the assigned memory address region only after the data processing circuitry first attempts to perform a memory access on a memory address within the assigned memory address region. The allocated portion of the cache memory is then initialized with the predefined initialization value.