A multi-use physical (PHY) architecture that includes a PHY connection that includes one or more bit lines and that is communicatively coupled to a first processor. The PHY connection is configurable to carry signals between the first processor and a second processor, or between the first processor and a memory. The one or more bit lines are configured to carry signals bi-directionally at a first voltage when the PHY connection is configured to carry signals between the first processor and the memory. The one or more bit lines are configured to carry signals uni-directionally at a second voltage when the PHY connection is configured to carry signals between the first processor and the second processor. The second voltage is different than the first voltage.