Invention Grant
- Patent Title: Thiazole derivative and use thereof as VAP-1 inhibitor
- Patent Title (中): 噻唑衍生物及其作为VAP-1抑制剂的用途
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Application No.: US12864773Application Date: 2009-01-30
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Publication No.: US08507690B2Publication Date: 2013-08-13
- Inventor: Tatsuya Matsukawa , Kazuhiro Masuzaki , Yosuke Kawai , Akiko Kawasaki , Akiko Akasaka , Makoto Takewaki
- Applicant: Tatsuya Matsukawa , Kazuhiro Masuzaki , Yosuke Kawai , Akiko Kawasaki , Akiko Akasaka , Makoto Takewaki
- Applicant Address: JP Tokyo
- Assignee: R-Tech Ueno, Ltd.
- Current Assignee: R-Tech Ueno, Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: JP2008-021588 20080131
- International Application: PCT/JP2009/052015 WO 20090130
- International Announcement: WO2009/096609 WO 20090806
- Main IPC: C07D277/38
- IPC: C07D277/38 ; A61K31/427 ; A61K31/426
Abstract:
The invention provides a thiazole derivative useful as a VAP-1 inhibitor, as well as a pharmaceutical agent for the prophylaxis or treatment of VAP-1 associated diseases and the like, a method of inhibiting VAP-1 in a subject, and a method for the prophylaxis or treatment of VAP-1 associated disease in a subject. The thiazole derivative is a compound represented by the formula (I): R1—NH—X—Y—Z wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20110015240A1 THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR Public/Granted day:2011-01-20
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