发明授权
- 专利标题： Processes for intermediates for macrocyclic compounds
- 专利标题（中）： 大环化合物中间体的方法
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申请号： US13036484申请日： 2011-02-28
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公开(公告)号： US08497242B2公开(公告)日： 2013-07-30
- 发明人: Éric Marsault , Kamel Benakli , Hamid R. Hoveyda , Mark L. Peterson , Sylvie Beaubien , Luc Ouellet , Carl St-Louis , Sophie Beauchemin
- 申请人： Éric Marsault , Kamel Benakli , Hamid R. Hoveyda , Mark L. Peterson , Sylvie Beaubien , Luc Ouellet , Carl St-Louis , Sophie Beauchemin
- 申请人地址： CA
- 专利权人： Tranzyme Pharma Inc.
- 当前专利权人： Tranzyme Pharma Inc.
- 当前专利权人地址： CA
- 代理机构： Myers Bigel Sibley & Sajovec, P.A.
- 主分类号： A61K38/25
- IPC分类号： A61K38/25
摘要：
The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: wherein R1, R2, R3, R4, R5, R6, n1, m, p Z1, Z2, and Z3 are as describe in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.
公开/授权文献
- US20110245459A1 Processes for Intermediates for Macrocyclic Compounds 公开/授权日：2011-10-06
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