发明授权
- 专利标题: Nucleosides for suppressing or reducing the development of resistance in cytostatic therapy
- 专利标题(中): 用于抑制或减少细胞抑制治疗中抗性发展的核苷
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申请号: US12377239申请日: 2007-08-13
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公开(公告)号: US08492537B2公开(公告)日: 2013-07-23
- 发明人: Rudolf Fahrig , Dieter Lohmann , Andreas Rolfs , Henrik Dieks , Janek Teubner , Jorg-Christian Heinrich
- 申请人: Rudolf Fahrig , Dieter Lohmann , Andreas Rolfs , Henrik Dieks , Janek Teubner , Jorg-Christian Heinrich
- 申请人地址: DE Dresden
- 专利权人: RESprotect GmbH
- 当前专利权人: RESprotect GmbH
- 当前专利权人地址: DE Dresden
- 代理机构: Leydig, Voit & Mayer, Ltd.
- 优先权: DE102006037786 20060811
- 国际申请: PCT/EP2007/007147 WO 20070813
- 国际公布: WO2008/017515 WO 20080214
- 主分类号: C07H19/00
- IPC分类号: C07H19/00 ; C07H19/048
摘要:
The invention relates to special nucleosides, for example, a nucleoside of the formula I, wherein R1-R5 are as described herein, and also to drugs which contain these nucleosides. Furthermore, the invention relates to the use of such nucleosides in a method for suppressing or reducing the formation of resistance in the case of cytotstatic treatment of a cancer patient.
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