发明授权
- 专利标题: Beta-glucosidase enzymes
- 专利标题(中): β-葡糖苷酶
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申请号: US12790079申请日: 2010-05-28
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公开(公告)号: US08486683B2公开(公告)日: 2013-07-16
- 发明人: Brian R. Scott , Chengsong Liu , James Lavigne , John J. Tomashek
- 申请人: Brian R. Scott , Chengsong Liu , James Lavigne , John J. Tomashek
- 申请人地址: CA Ontario
- 专利权人: Iogen Energy Corporation
- 当前专利权人: Iogen Energy Corporation
- 当前专利权人地址: CA Ontario
- 代理机构: Fitzpatrick, Cella, Harper & Scinto
- 主分类号: C12N9/42
- IPC分类号: C12N9/42 ; C12N1/20 ; C12N15/00 ; C12P19/00
摘要:
Provided are modified beta-glucosidase enzymes, derived from the Trichoderma reesei Cel3A beta-glucosidase, that exhibit improvements in one or more kinetic parameters (KG, KG2, kcat) comprising amino acid substitutions at one or more of positions 43, 101, 260 and 543. Also provided are genetic constructs comprising nucleotide sequences encoding for modified beta-glucosidase enzymes, methods for the production of modified beta-glucosidase enzymes from host strains and the use of the modified beta-glucosidase enzymes in the hydrolysis of cellulose.
公开/授权文献
- US20100304438A1 NOVEL BETA-GLUCOSIDASE ENZYMES 公开/授权日:2010-12-02
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