发明授权
- 专利标题： Heteroaryl dihydroindolones as kinase inhibitors
- 专利标题（中）： 杂芳基二氢吲哚酮作为激酶抑制剂
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申请号： US13150543申请日： 2011-06-01
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公开(公告)号： US08455535B2公开(公告)日： 2013-06-04
- 发明人: Sougato Boral , Xialing Guo , Shimiao Wang , Julie A. Wurster , Thomas C. Malone
- 申请人： Sougato Boral , Xialing Guo , Shimiao Wang , Julie A. Wurster , Thomas C. Malone
- 申请人地址： US CA Irvine
- 专利权人： Allergan, Inc.
- 当前专利权人： Allergan, Inc.
- 当前专利权人地址： US CA Irvine
- 代理商 Krishna G. Banerjee
- 主分类号： A61K31/4015
- IPC分类号： A61K31/4015 ; C07D209/34
摘要：
The present invention provides a compound represented by the formula: wherein ring systems A and B, and the variables R1, b, R6, Y, Z, X, R and a are defined in the specification. The compounds of the present invention may be used in a method for treating diseases related to unregulated tyrosine kinase signal transduction, such as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, and metabolic diseases.
公开/授权文献
- US20110257238A1 Heteroaryl Dihydroindolones as Kinase Inhibitors 公开/授权日：2011-10-20
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