发明授权
US08431357B2 Method and apparatus for measuring analyte transport across barriers using x-ray fluorescence
有权
使用X射线荧光测量跨屏障的分析物传输的方法和装置
- 专利标题： Method and apparatus for measuring analyte transport across barriers using x-ray fluorescence
- 专利标题（中）： 使用X射线荧光测量跨屏障的分析物传输的方法和装置
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申请号： US12496532申请日： 2009-07-01
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公开(公告)号： US08431357B2公开(公告)日： 2013-04-30
- 发明人: Eva R. Birnbaum , Rebecca L. E. Miller , Lori J. Peterson , Jennifer A. Berger , Benjamin P. Warner
- 申请人： Eva R. Birnbaum , Rebecca L. E. Miller , Lori J. Peterson , Jennifer A. Berger , Benjamin P. Warner
- 申请人地址： US NM Los Alamas
- 专利权人： Caldera Pharmaceuticals, Inc.
- 当前专利权人： Caldera Pharmaceuticals, Inc.
- 当前专利权人地址： US NM Los Alamas
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; G01N21/76 ; G01N23/223
摘要：
The present invention includes a method and apparatus for measuring the removal of analyte from a cell. One or more cells are provided, comprising at least 10 picograms of an analyte within a volume defined by the area of an x-ray excitation beam and a depth of a depth of five times the 1/e attenuation depth for at least one characteristic x-ray signal of the analyte as attenuated by water. At least a of portion of the analyte is removed from the cells; and the analyte is measured using x-ray fluorescence.
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