Invention Grant
- Patent Title: Arene connected polyamine macrocyclic derivatives, preparation methods and pharmaceutical uses thereof
- Patent Title (中): 芳烃连接多胺大环衍生物,其制备方法和药物用途
-
Application No.: US12601867Application Date: 2008-05-30
-
Publication No.: US08420626B2Publication Date: 2013-04-16
- Inventor: Song Li , Jing Su , Yao Liu , Junhai Xiao , Lili Wang , Wu Zhong , Zhibing Zheng , Yunde Xie , Xingzhou Li , Guoming Zhao , Xiaokui Wang , Xinbo Zhou , Hongying Liu
- Applicant: Song Li , Jing Su , Yao Liu , Junhai Xiao , Lili Wang , Wu Zhong , Zhibing Zheng , Yunde Xie , Xingzhou Li , Guoming Zhao , Xiaokui Wang , Xinbo Zhou , Hongying Liu
- Applicant Address: CN Beijing
- Assignee: Beijing Molecule Science and Technology Co., Ltd.
- Current Assignee: Beijing Molecule Science and Technology Co., Ltd.
- Current Assignee Address: CN Beijing
- Agency: MacMillan, Sobanski & Todd, LLC
- Priority: CN200710106045 20070530
- International Application: PCT/CN2008/001070 WO 20080530
- International Announcement: WO2008/148302 WO 20081211
- Main IPC: A61K31/33
- IPC: A61K31/33 ; C07D245/00 ; C07D245/02 ; C07D245/04 ; C07D245/06 ; C07D487/02

Abstract:
The present invention relates to arene connected polyamine macrocyclic derivatives represented by general formula I, pharmaceutically acceptable salts or hydrates thereof which have anti-HIV activities, in which the definitions of substituents are as defined in the description; to preparation methods of the compounds of formula I; to pharmaceutical compositions containing the compounds of formula I or their pharmaceutically acceptable salts or hydrates; to the use of the compounds of formula I or their pharmaceutically acceptable salts or hydrates for the preparation of a medicament for the treatment and prevention of HIV-associated diseases.
Public/Granted literature
- US20100179116A1 Arene Connected Polyamine Macrocyclic Derivatives, Preparation Methods and Pharmaceutical Uses Thereof Public/Granted day:2010-07-15
Information query