Invention Grant
US08420626B2 Arene connected polyamine macrocyclic derivatives, preparation methods and pharmaceutical uses thereof 有权
芳烃连接多胺大环衍生物,其制备方法和药物用途

Arene connected polyamine macrocyclic derivatives, preparation methods and pharmaceutical uses thereof
Abstract:
The present invention relates to arene connected polyamine macrocyclic derivatives represented by general formula I, pharmaceutically acceptable salts or hydrates thereof which have anti-HIV activities, in which the definitions of substituents are as defined in the description; to preparation methods of the compounds of formula I; to pharmaceutical compositions containing the compounds of formula I or their pharmaceutically acceptable salts or hydrates; to the use of the compounds of formula I or their pharmaceutically acceptable salts or hydrates for the preparation of a medicament for the treatment and prevention of HIV-associated diseases.
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