发明授权
- 专利标题: Modulation of TRPV expression levels
- 专利标题(中): 调节TRPV表达水平
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申请号: US12090426申请日: 2006-10-20
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公开(公告)号: US08354385B2公开(公告)日: 2013-01-15
- 发明人: Maria Del Carmen Acosta Boj , Juana Gallar Martinez , Angela Sesto Yague , Carlos Belmonte Martinez , Ana Isabel Jimenez Anton , Maria Concepcion Jimenez Gomez
- 申请人: Maria Del Carmen Acosta Boj , Juana Gallar Martinez , Angela Sesto Yague , Carlos Belmonte Martinez , Ana Isabel Jimenez Anton , Maria Concepcion Jimenez Gomez
- 申请人地址: ES Madrid
- 专利权人: Sylentis S.A.U.
- 当前专利权人: Sylentis S.A.U.
- 当前专利权人地址: ES Madrid
- 代理机构: King & Spalding
- 代理商 Margaret B. Brivanlou
- 优先权: GB0521351.7 20051020
- 国际申请: PCT/GB2006/050342 WO 20061020
- 国际公布: WO2007/045930 WO 20070426
- 主分类号: A61K48/00
- IPC分类号: A61K48/00
摘要:
The present invention relates to methods and compositions for the treatment and/or the prevention of conditions related to high levels of expression and/or activity of the transient receptor potential vanilloid-1 (TRPV1). Amongst others, the conditions to be treated are eye conditions such as discomfort and altered sensitivity of the cornea following refractive surgery, use of contact lenses, dry eyes and diabetic retinopathy.
公开/授权文献
- US20100286230A1 MODULATION OF TRPV EXPRESSION LEVELS 公开/授权日:2010-11-11
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