Invention Grant
US08329465B2 Recombinant cell clones having increased stability and methods of making and using the same
有权
具有增加的稳定性的重组细胞克隆及其制备和使用方法
- Patent Title: Recombinant cell clones having increased stability and methods of making and using the same
- Patent Title (中): 具有增加的稳定性的重组细胞克隆及其制备和使用方法
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Application No.: US12986111Application Date: 2011-01-06
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Publication No.: US08329465B2Publication Date: 2012-12-11
- Inventor: Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- Applicant: Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- Applicant Address: AT Vienna
- Assignee: Baxter Innovations GmbH
- Current Assignee: Baxter Innovations GmbH
- Current Assignee Address: AT Vienna
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: AT1073/97 19970620
- Main IPC: C12N15/85
- IPC: C12N15/85 ; C12N15/09 ; C12P21/00
Abstract:
Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
Public/Granted literature
- US20110104758A1 RECOMBINANT CELL CLONES HAVING INCREASED STABILITY AND METHODS OF MAKING AND USING THE SAME Public/Granted day:2011-05-05
Information query
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