Invention Grant
- Patent Title: Cathepsin cysteine protease inhibitors
- Patent Title (中): 组织蛋白酶半胱氨酸蛋白酶抑制剂
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Application No.: US13115462Application Date: 2011-05-25
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Publication No.: US08318748B2Publication Date: 2012-11-27
- Inventor: Christopher I. Bayly , Cameron Black , Serge Leger , Chun Sing Li , Dan McKay , Christophe Mellon , Jacques Yves Gauthier , Vouy-Linh Truong , Cheuk Lau , Michel Therien , Michael J. Green , Bernard L. Hirschbein , James William Janc , James T. Palmer , Chitra Baskaran
- Applicant: Christopher I. Bayly , Cameron Black , Serge Leger , Chun Sing Li , Dan McKay , Christophe Mellon , Jacques Yves Gauthier , Vouy-Linh Truong , Cheuk Lau , Michel Therien , Michael J. Green , Bernard L. Hirschbein , James William Janc , James T. Palmer , Chitra Baskaran
- Applicant Address: US NJ Rahway US CA South San Francisco
- Assignee: Merck, Sharp & Dohme Corp.,Axys Pharmaceuticals, Inc.
- Current Assignee: Merck, Sharp & Dohme Corp.,Axys Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Rahway US CA South San Francisco
- Agent Nicole M. Beeler; Gerard M. Devlin
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; A61K31/66 ; A61K31/44 ; A61K31/445 ; A61K31/425 ; A61K31/415
Abstract:
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
Public/Granted literature
- US20110230446A1 CATHEPSIN CYSTEINE PROTEASE INHIBITORS Public/Granted day:2011-09-22
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