发明授权
- 专利标题： Methods and systems of using exosomes for determining phenotypes
- 专利标题（中）： 使用外来体确定表型的方法和系统
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申请号： US13009393申请日： 2011-01-19
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公开(公告)号： US08278059B2公开(公告)日： 2012-10-02
- 发明人: Michael Klass , Christine Kuslich , George Poste
- 申请人： Michael Klass , Christine Kuslich , George Poste
- 申请人地址： LU Luxembourg
- 专利权人： Caris Life Sciences Luxembourg Holdings, S.A.R.L.
- 当前专利权人： Caris Life Sciences Luxembourg Holdings, S.A.R.L.
- 当前专利权人地址： LU Luxembourg
- 代理机构： Wilson Sonsini Goodrich & Rosati
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C12Q1/68
摘要：
Exosomes can be used for detecting biomarkers for diagnostic, therapy-related or prognostic methods to identify phenotypes, such as a condition or disease, for example, the stage or progression of a disease. Cell-of-origin exosomes can be used in profiling of physiological states or determining phenotypes. Biomarkers or markers from cell-of-origin specific exosomes can be used to determine treatment regimens for diseases, conditions, disease stages, and stages of a condition, and can also be used to determine treatment efficacy. Markers from cell-of-origin specific exosomes can also be used to identify conditions of diseases of unknown origin.
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