发明授权
- 专利标题: Hepatocyte growth factor (HGF) binding proteins
- 专利标题(中): 肝细胞生长因子(HGF)结合蛋白
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申请号: US13051474申请日: 2011-03-18
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公开(公告)号: US08268315B2公开(公告)日: 2012-09-18
- 发明人: May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
- 申请人: May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
- 申请人地址: US MA Cambridge
- 专利权人: AVEO Pharmaceuticals, Inc.
- 当前专利权人: AVEO Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Goodwin Procter LLP
- 主分类号: A61K39/395
- IPC分类号: A61K39/395
摘要:
The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
公开/授权文献
- US20110236377A1 Hepatocyte Growth Factor (HGF) Binding Proteins 公开/授权日:2011-09-29
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