The invention provides load-resisting segments (e.g., panels or frames for openings) for transmitting loads through a building structure. In the context of a wall, the load-resisting segments transmit shear loads downward to structural elements below the wall, such as to a building foundation. The load-resisting segments may comprise a truss configuration, i.e., an assembly of members forming a rigid framework. Each load-resisting segment can include web members and pairs of truss plates secured to sides of the segment to secure connections of the web members to each other and to other members. The wall segments can include beam-separation blocks that reduce truss plate failure by spacing apart the ends of two web members bearing against a chord or post to position the intersection point of the load paths of the web members with the load path of the chord or post. Some of the truss plates can include strips of material to provide additional resistance to tearing of the truss plate due to loads experienced by the truss plate. Some of the load-resisting segments, particularly frames for doors or windows, may include compression plates that prevent point-loading of studs or chords against transversely oriented members. For example, a truss frame may include compression plates between ends of its columns and surfaces of a header or sill structure.