Invention Grant
US08198331B2 Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
有权
11-β-羟基类固醇脱氢酶1型酶的抑制剂
- Patent Title: Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
- Patent Title (中): 11-β-羟基类固醇脱氢酶1型酶的抑制剂
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Application No.: US12390286Application Date: 2009-02-20
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Publication No.: US08198331B2Publication Date: 2012-06-12
- Inventor: R. Scott Bitner , Kaitlin E. Browman , Michael E. Brune , Steven Fung , Peer B. Jacobson , Lynne E. Rueter , Marina I. Strakhova , Jiahong Wang , Jeffrey J. Rohde , Qi Shuai , James T. Link , Jyoti R. Patel , Jurgen Dinges , Bryan K. Sorensen , Hong Yong , Vince S. Yeh , Ravi Kurukulasuriya
- Applicant: R. Scott Bitner , Kaitlin E. Browman , Michael E. Brune , Steven Fung , Peer B. Jacobson , Lynne E. Rueter , Marina I. Strakhova , Jiahong Wang , Jeffrey J. Rohde , Qi Shuai , James T. Link , Jyoti R. Patel , Jurgen Dinges , Bryan K. Sorensen , Hong Yong , Vince S. Yeh , Ravi Kurukulasuriya
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agency: Klintworth & Rozenblat IP LLC
- Main IPC: A61K31/16
- IPC: A61K31/16

Abstract:
The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.
Public/Granted literature
- US20090176783A1 INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME Public/Granted day:2009-07-09
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