Invention Grant
US08178496B2 Photoreactive regulator of glutamate receptor function and methods of use thereof
有权
谷氨酸受体功能的光反应调节剂及其使用方法
- Patent Title: Photoreactive regulator of glutamate receptor function and methods of use thereof
- Patent Title (中): 谷氨酸受体功能的光反应调节剂及其使用方法
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Application No.: US12338880Application Date: 2008-12-18
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Publication No.: US08178496B2Publication Date: 2012-05-15
- Inventor: Dirk Trauner , Ehud Y. Isacoff , Matthew Volgraf , Pablo Ignacio Gorostiza Langa
- Applicant: Dirk Trauner , Ehud Y. Isacoff , Matthew Volgraf , Pablo Ignacio Gorostiza Langa
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis LLP.
- Agent Paula A. Borden
- Main IPC: C07C323/12
- IPC: C07C323/12 ; A61A38/00
Abstract:
The present invention provides a synthetic regulator of glutamate receptor function, which regulator is a light-sensitive (photoreactive) regulator. The present invention further provides a light-regulated glutamate receptor that includes a subject synthetic regulator non-covalently associated with the glutamate receptor. Also provided are cells and membranes comprising a subject light-regulated glutamate receptor. The present invention further provides methods of modulating glutamate receptor function, involving use of light. The present invention further provides methods of identifying agents that modulate glutamate receptor function.
Public/Granted literature
- US20090181454A1 PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF Public/Granted day:2009-07-16
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