发明授权
- 专利标题： Glycoprotein VI and uses thereof
- 专利标题（中）： 糖蛋白Ⅵ及其用途
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申请号： US12690710申请日： 2010-01-20
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公开(公告)号： US08137923B2公开(公告)日： 2012-03-20
- 发明人: Samantha J. Busfield , Jean-Luc Villeval
- 申请人： Samantha J. Busfield , Jean-Luc Villeval
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Foley Hoag LLP
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07K16/18 ; C07K16/28 ; C12P21/08
摘要：
The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein VI, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
公开/授权文献
- US20100261200A1 Glycoprotein VI and Uses Thereof 公开/授权日：2010-10-14
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