A sample and hold circuit is disclosed that provides longer hold times. An analog multiplexer circuit is also disclosed that exhibits low switch leakage. The analog multiplexer circuit comprises a shared node, a plurality of input circuits, a control input for selecting one or more of the plurality of input circuits, and an amplifier coupled to the shared node. Each input circuit comprises an input node, a primary input switch for selectively coupling an input to the input node, and a secondary input switch for selectively coupling the input node to the shared node, wherein the secondary input switch comprises one or more transistor switches. The parasitic drain and source diodes of one or more transistor switches in secondary input switch in a selected input circuit are coupled to a voltage that is distinct from an input signal of the selected input circuit. For input circuits not selected, the parasitic drain and source diodes of secondary input switch transistor switches are coupled to an output of the amplifier.