Invention Grant
- Patent Title: Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
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Application No.: US11525213Application Date: 2006-09-22
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Publication No.: US08106066B2Publication Date: 2012-01-31
- Inventor: Richard Schumacher , Mihaela Diana Danca , Jianguo Ma , Brian Herbert , True Minh Nguyen , Wenge Xie , Ashok Tehim
- Applicant: Richard Schumacher , Mihaela Diana Danca , Jianguo Ma , Brian Herbert , True Minh Nguyen , Wenge Xie , Ashok Tehim
- Applicant Address: US NJ Montvale
- Assignee: Memory Pharmaceuticals Corporation
- Current Assignee: Memory Pharmaceuticals Corporation
- Current Assignee Address: US NJ Montvale
- Agency: Millen, White, Zelano & Branigan, P.C.
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D221/02 ; C07D217/22
Abstract:
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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