发明授权
US07977477B2 Benzimidazole derivatives and their use as protein kinase inhibitors
失效
苯并咪唑衍生物及其作为蛋白激酶抑制剂的用途
- 专利标题: Benzimidazole derivatives and their use as protein kinase inhibitors
- 专利标题(中): 苯并咪唑衍生物及其作为蛋白激酶抑制剂的用途
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申请号: US10564166申请日: 2004-07-05
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公开(公告)号: US07977477B2公开(公告)日: 2011-07-12
- 发明人: Valerio Berdini , Michael Alistair O'Brien , Maria Grazia Carr , Theresa Rachel Early , Eva Figueroa Navarro , Adrian Liam Gill , Steven Howard , Gary Trewartha , Alison Jo-Anne Woolford , Andrew James Woodhead , Paul Wyatt
- 申请人: Valerio Berdini , Michael Alistair O'Brien , Maria Grazia Carr , Theresa Rachel Early , Eva Figueroa Navarro , Adrian Liam Gill , Steven Howard , Gary Trewartha , Alison Jo-Anne Woolford , Andrew James Woodhead , Paul Wyatt
- 申请人地址: GB Cambridge
- 专利权人: Astex Therapeutics, Limited
- 当前专利权人: Astex Therapeutics, Limited
- 当前专利权人地址: GB Cambridge
- 代理机构: Heslin Rothenberg Farley & Mesiti P.C.
- 优先权: GB0315657.7 20030703; GB0324919.0 20031024
- 国际申请: PCT/GB2004/002824 WO 20040705
- 国际公布: WO2005/002552 WO 20050113
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; A61K31/4184 ; C07D413/14
摘要:
The invention provides compounds of the formula (I): The compounds have activity against cyclin dependent kinases, glycogen synthase kinase and Auroa kinases and are therefore useful to treat cancer and viral diseases.
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