发明授权
US07977366B2 Treating an inflammatory disorder or inhibiting respiratory burst in adherent neutrophils with chemical inhibitors of neutrophil activation
失效
用嗜中性粒细胞活化化学抑制剂治疗粘连嗜中性粒细胞炎症性疾病或抑制呼吸爆发
- 专利标题： Treating an inflammatory disorder or inhibiting respiratory burst in adherent neutrophils with chemical inhibitors of neutrophil activation
- 专利标题（中）： 用嗜中性粒细胞活化化学抑制剂治疗粘连嗜中性粒细胞炎症性疾病或抑制呼吸爆发
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申请号： US10575683申请日： 2004-10-14
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公开(公告)号： US07977366B2公开(公告)日： 2011-07-12
- 发明人: Hyunsil Han , Gang Lin , Carl Nathan
- 申请人： Hyunsil Han , Gang Lin , Carl Nathan
- 申请人地址： US NY Ithaca
- 专利权人： Cornell Research Foundation, Inc.
- 当前专利权人： Cornell Research Foundation, Inc.
- 当前专利权人地址： US NY Ithaca
- 代理机构： LeClairRyan
- 国际申请： PCT/US2004/033914 WO 20041014
- 国际公布： WO2005/037213 WO 20050428
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; A61K31/41 ; A61P37/00
摘要：
The present invention relates to a method of treating an inflammatory disorder in a subject with an effective amount of compound having the general formula (I) as described in the present application, under conditions effective to treat the inflammatory disorder. The present invention also relates to a method of inhibiting respiratory burst in neutrophils without inhibiting degranulation in or bacterial killing by the neutrophils by contacting neutrophils with the compounds described above.
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