发明授权
- 专利标题： Heteroaryl dihydroindolones as kinase inhibitors
- 专利标题（中）： 杂芳基二氢吲哚酮作为激酶抑制剂
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申请号： US11687408申请日： 2007-03-16
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公开(公告)号： US07977351B2公开(公告)日： 2011-07-12
- 发明人: Sougato Boral , Xialing Guo , Shimiao Wang , Julie A. Wurster , Thomas C. Malone
- 申请人： Sougato Boral , Xialing Guo , Shimiao Wang , Julie A. Wurster , Thomas C. Malone
- 申请人地址： US CA Irvine
- 专利权人： Allergan, Inc.
- 当前专利权人： Allergan, Inc.
- 当前专利权人地址： US CA Irvine
- 代理机构： Allergan, Inc.
- 代理商 Joel B. German; Debra D. Condino
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; C07D471/04
摘要：
The present invention provides a compound represented by the formula: wherein the variables R1, b, R6, Y, Z, X, R and a are defined in the specification. Said compound may be used in a method for treating diseases related to unregulated tyrosine kinase signal transduction, wherein said disease is selected from the group consisting of cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, and metabolic diseases.
公开/授权文献
- US20080045526A1 HETEROARYL DIHYDROINDOLONES AS KINASE INHIBITORS 公开/授权日：2008-02-21
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