Invention Grant
- Patent Title: Cathepsin cysteine protease inhibitors
- Patent Title (中): 组织蛋白酶半胱氨酸蛋白酶抑制剂
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Application No.: US12082104Application Date: 2008-04-08
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Publication No.: US07973037B2Publication Date: 2011-07-05
- Inventor: Christopher I. Bayly , Cameron Black , Serge Leger , Chun Sing Li , Dan McKay , Christophe Mellon , Jacques Yves Gauthier , Vouy-Linh Truong , Cheuk Lau , Michel Therien , Michael J. Green , Bernard L. Hirschbein , James William Janc , James T. Palmer , Chitra Baskaran
- Applicant: Christopher I. Bayly , Cameron Black , Serge Leger , Chun Sing Li , Dan McKay , Christophe Mellon , Jacques Yves Gauthier , Vouy-Linh Truong , Cheuk Lau , Michel Therien , Michael J. Green , Bernard L. Hirschbein , James William Janc , James T. Palmer , Chitra Baskaran
- Applicant Address: US CA South San Francisco CA Quebec
- Assignee: Axys Pharmaceuticals, Inc.,Merck Canada Inc.
- Current Assignee: Axys Pharmaceuticals, Inc.,Merck Canada Inc.
- Current Assignee Address: US CA South San Francisco CA Quebec
- Agent Nicole M. Beeler; David A. Muthard
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A61K31/497 ; A61K31/435 ; A61K31/385 ; C07D265/30 ; C07D241/04 ; C07D211/08 ; C07D333/02 ; C07D255/03
Abstract:
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
Public/Granted literature
- US20080188529A1 Cathepsin cysteine protease inhibitors Public/Granted day:2008-08-07
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