发明授权
US07910351B2 Mutant F. turlarensis strain and uses thereof 有权
突变体F.格朗汉斯菌株及其用途

Mutant F. turlarensis strain and uses thereof
摘要:
A mutant strain of Francisella tularensis has attenuated virulence and has a mutation in the gene coding for a putative peroxynitrite resistance protein A (prpA) which prevents normal function of the protein. The mutant is useful as a vaccine against type A and B virulent strains of F. tularensis, and is produced by obtaining a virulent F. tularensis strain and mutating the gene, FTT0918, that codes for prpA.
公开/授权文献
信息查询
0/0