发明授权
- 专利标题: Alleles of the PRPD1 gene from coryneform bacteria
- 专利标题(中): 来自棒状细菌的PRPD1基因的等位基因
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申请号: US11923942申请日: 2007-10-25
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公开(公告)号: US07893231B2公开(公告)日: 2011-02-22
- 发明人: Brigitte Bathe , Caroline Kreutzer , Georg Thierbach
- 申请人: Brigitte Bathe , Caroline Kreutzer , Georg Thierbach
- 申请人地址: DE Duesseldorf
- 专利权人: Evonik Degussa GmbH
- 当前专利权人: Evonik Degussa GmbH
- 当前专利权人地址: DE Duesseldorf
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权: DE102006050489 20061026
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; C12P21/06 ; C12P21/04 ; C12N1/20 ; C12N15/00
摘要:
An isolated mutant of coryneform bacteria comprising a gene encodes a polypeptide having 2-methylcitrate dehydratase activity, where the polypeptide comprises an amino acid sequence in which one of the proteinogenic amino acids except L-proline is present at position 272 or a corresponding or comparable position. In addition, an isolated polynucleotide encoding a polypeptide having 2-methylcitrate dehydratase enzymic activity, which comprises at position 272 of the amino acid sequence or a corresponding or comparable position a proteinogenic amino acid except L-proline is described. A method for producing a recombinant coryneform bacterium and L-amino acids. A recombinant microorganism, L-Lysine-containing feed additive, and L-Tryptophan-containing feed additive is also described.
公开/授权文献
- US20080274265A1 ALLELES OF THE PRPD1 GENE FROM CORYNEFORM BACTERIA 公开/授权日:2008-11-06
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