A low permeability hose system for providing an impermeable length of tube to transfer fluids that is flexible. The low permeability hose system generally includes a hose defining a fluid passage and an impermeable layer attached to the exterior surface of the hose. The impermeable layer is comprised of an aluminum coated heat sealable film that is impermeable to both liquids and gases. A protective layer may be attached to the impermeable layer to protect the impermeable layer from damage.