发明授权
- 专利标题： RNA interference induction element and use thereof
- 专利标题（中）： RNA干扰诱导元件及其用途
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申请号： US11920508申请日： 2006-05-15
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公开(公告)号： US07847089B2公开(公告)日： 2010-12-07
- 发明人: Kojiro Ishii , Kohta Takahashi
- 申请人： Kojiro Ishii , Kohta Takahashi
- 申请人地址： JP Fukuoka JP Saitama
- 专利权人： Kurume University,Japan Science and Technology Agency
- 当前专利权人： Kurume University,Japan Science and Technology Agency
- 当前专利权人地址： JP Fukuoka JP Saitama
- 代理机构： Wenderoth, Lind & Ponack, L.L.P.
- 优先权： JP2005-145876 20050518
- 国际申请： PCT/JP2006/310079 WO 20060515
- 国际公布： WO2006/123800 WO 20061123
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; A01N43/04 ; A61K31/70
摘要：
The present invention provides an RNA interference induction element containing a nucleotide sequence selected from among the nucleotide sequences (a) to (c) below: (a) a nucleotide sequence containing SEQ ID NO:1 or a sequence complementary thereto; (b) a nucleotide sequence containing at least 15 continuous nucleotides present in the nucleotide sequence (a) above, and possessing RNA interference induction potential; (c) a nucleotide sequence having a homology of at least 70% to any one of the nucleotide sequences (a) and (b) above, and possessing RNA interference induction potential. Using the RNA interference induction element of the present invention, it is easily possible to knock down a desired target gene, and to produce a siRNA for a desired target gene.
公开/授权文献
- US20090215644A1 Rna interference induction element and use thereof 公开/授权日：2009-08-27
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