发明授权
- 专利标题： Moraxella catarrhalis protein, nucleic acid sequence and uses thereof
- 专利标题（中）： 卡他莫拉菌素，核酸序列及其用途
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申请号： US12004502申请日： 2007-12-21
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公开(公告)号： US07846451B2公开(公告)日： 2010-12-07
- 发明人: Kenneth Tucker , Ulrich F. Tillman
- 申请人： Kenneth Tucker , Ulrich F. Tillman
- 申请人地址： US MD Gaithersburg
- 专利权人： Emergent Product Development Gaithersburg, Inc.
- 当前专利权人： Emergent Product Development Gaithersburg, Inc.
- 当前专利权人地址： US MD Gaithersburg
- 代理机构： K&L Gates LLP
- 主分类号： A61K39/02
- IPC分类号： A61K39/02 ; C12P21/04 ; C07H21/04 ; C07K14/00
摘要：
The invention discloses the Moraxella catarrhalis outer membrane protein polypeptide and polypeptides derived therefrom (collectively “OMP21”), nucleotide sequences encoding said OMP21, and antibodies that specifically bind OMP21. Also disclosed are pharmaceutical compositions including prophylactic or therapeutic compositions, which may be immunogenic compositions including vaccines, comprising OMP21, antibodies thereto or nucleotides encoding same. The invention additionally discloses methods of inducing an immune response to M. catarrhalis and OMP21 in an animal, preferably a human, methods of treating and methods of diagnosing Moraxella infections in an animal, preferably a human, and kits therefor.
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