Invention Grant
- Patent Title: Method for producing flavan derivatives
- Patent Title (中): 黄烷衍生物的生产方法
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Application No.: US12282293Application Date: 2007-03-09
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Publication No.: US07820835B2Publication Date: 2010-10-26
- Inventor: Keisuke Suzuki , Ken Ohmori , Takashi Higuchi
- Applicant: Keisuke Suzuki , Ken Ohmori , Takashi Higuchi
- Applicant Address: JP Tokyo
- Assignee: Tokyo Institute of Technology
- Current Assignee: Tokyo Institute of Technology
- Current Assignee Address: JP Tokyo
- Agency: Venable LLP
- Agent Michael A. Sartori
- Priority: JP2006-106895 20060310
- International Application: PCT/JP2007/054669 WO 20070309
- International Announcement: WO2007/105629 WO 20070920
- Main IPC: C07D311/62
- IPC: C07D311/62

Abstract:
The present invention provides a method for producing flavan derivatives having various substituent groups with controlling the stereochemistry. The method of the present invention includes the steps of: hydratively condensing a phenol compound expressed by formula (I) and an alcohol compound expressed by formula (II) to from an epoxide compound of formula (III); opening the epoxy ring of the epoxide compound of formula (III) to form an iodine-containing compound of formula (IV); and cyclizing the iodine-containing compound to form the flavan derivative of formula (V).
Public/Granted literature
- US20090099374A1 METHOD FOR PRODUCING FLAVAN DERIVATIVE Public/Granted day:2009-04-16
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