发明授权
US07803758B2 I kappa B kinase complex as a target for the treatment of Huntington's disease
有权
我以Kappa B激酶复合物作为治疗亨廷顿病的靶标
- 专利标题： I kappa B kinase complex as a target for the treatment of Huntington's disease
- 专利标题（中）： 我以Kappa B激酶复合物作为治疗亨廷顿病的靶标
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申请号： US11869501申请日： 2007-10-09
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公开(公告)号： US07803758B2公开(公告)日： 2010-09-28
- 发明人: Ali Khoshnan , Paul H. Patterson
- 申请人： Ali Khoshnan , Paul H. Patterson
- 申请人地址： US CA Pasadena
- 专利权人： California Institute of Technology
- 当前专利权人： California Institute of Technology
- 当前专利权人地址： US CA Pasadena
- 代理机构： Knobbe, Martens, Olson & Bear, LLP
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K49/00 ; G01N33/53 ; G01N33/567 ; C12Q1/66
摘要：
The present invention provides methods and compositions for protecting cells from the toxicity of mutant huntingtin (Htt) protein and for treatment of Huntington's disease (HD). The methods generally involve administering to cells or a patient an effective amount of an IKK inhibitor. In addition, methods are provided for identifying therapeutics for the treatment of HD.
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