发明授权
- 专利标题: Modulation of HIF1-beta expression
- 专利标题(中): 调节HIF1-β表达
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申请号: US12578468申请日: 2009-10-13
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公开(公告)号: US07799764B2公开(公告)日: 2010-09-21
- 发明人: Eric G. Marcusson , Scott W. Henry , Youngsoo Kim , Kenneth Dobie
- 申请人: Eric G. Marcusson , Scott W. Henry , Youngsoo Kim , Kenneth Dobie
- 申请人地址: US CA Carlsbad
- 专利权人: Isis Pharmaceuticals, Inc.
- 当前专利权人: Isis Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Carlsbad
- 代理机构: Knobbe Martens Olson & Bear LLP
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12Q1/68 ; C12N5/00
摘要:
Compounds, compositions and methods are provided for modulating the expression of HIF1-beta. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1-beta. Methods of using these compounds for modulation of HIF1-beta expression and for diagnosis and treatment of diseases and conditions associated with expression of HIF1-beta are provided.
公开/授权文献
- US20100113573A1 MODULATION OF HIF1 BETA EXPRESSION 公开/授权日:2010-05-06
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