发明授权
- 专利标题: Carbostyril compound
- 专利标题(中): 碳青霉烯化合物
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申请号: US10582014申请日: 2005-09-26
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公开(公告)号: US07777038B2公开(公告)日: 2010-08-17
- 发明人: Takeshi Kuroda , Takahito Yamauchi , Tomoichi Shinohara , Kunio Oshima , Chiharu Kitajima , Hitoshi Nagao , Tae Fukushima , Takahiro Tomoyasu , Hironobu Ishiyama , Kazuhide Ohta , Masaaki Takano , Takumi Sumida
- 申请人: Takeshi Kuroda , Takahito Yamauchi , Tomoichi Shinohara , Kunio Oshima , Chiharu Kitajima , Hitoshi Nagao , Tae Fukushima , Takahiro Tomoyasu , Hironobu Ishiyama , Kazuhide Ohta , Masaaki Takano , Takumi Sumida
- 申请人地址: JP Tokyo
- 专利权人: Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人: Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- 优先权: JP2004-282814 20040928
- 国际申请: PCT/JP2005/018217 WO 20050926
- 国际公布: WO2006/035954 WO 20060406
- 主分类号: C07D215/38
- IPC分类号: C07D215/38
摘要:
The present invention provides a carbostyril compound represented by General Formula (1) or a salt thereof, wherein A is a direct bond, a lower alkylene group, or a lower alkylidene group; X is an oxygen atom or a sulfur atom; R4 and R5 each represent a hydrogen atom; the bond between the 3 and 4 positions of the carbostyril skeleton is a single bond or a double bond; R1 is a hydrogen atom, etc; R2 is a hydrogen atom, etc; and R3 is a hydrogen atom, etc. The carbostyril compound or salt thereof of the present invention induces the production of TFF, and thus is usable for the treatment and/or prevention of disorders such as alimentary tract diseases, oral diseases, upper respiratory tract diseases, respiratory tract diseases, eye diseases, cancers, and wounds.
公开/授权文献
- US20070179173A1 Carbostyril compound 公开/授权日:2007-08-02
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