发明授权
US07745604B2 Upstream control elements of the proopiomelanocortin gene and their use
有权
proopiomelanocortin基因的上游控制元件及其用途
- 专利标题： Upstream control elements of the proopiomelanocortin gene and their use
- 专利标题（中）： proopiomelanocortin基因的上游控制元件及其用途
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申请号： US11503426申请日： 2006-08-10
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公开(公告)号： US07745604B2公开(公告)日： 2010-06-29
- 发明人: Malcolm J. Low , Marcelo Rubinstein , Flavio Silva Junqueira de Souza
- 申请人： Malcolm J. Low , Marcelo Rubinstein , Flavio Silva Junqueira de Souza
- 申请人地址： US OR Portland
- 专利权人： Oregon Health & Science University
- 当前专利权人： Oregon Health & Science University
- 当前专利权人地址： US OR Portland
- 代理机构： Klarquist Sparkman, LLP
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12N15/00 ; C12N5/00
摘要：
The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein.
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