发明授权
- 专利标题: Method for preventing, or reducing the severity of, graft-versus-host disease using pluri-differentiated mesenchymal progenitor cells
- 专利标题(中): 使用分裂的间充质祖细胞预防或降低移植物抗宿主病的严重性的方法
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申请号: US11999055申请日: 2007-12-04
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公开(公告)号: US07691415B2公开(公告)日: 2010-04-06
- 发明人: Beerelli Seshi
- 申请人: Beerelli Seshi
- 申请人地址: US FL Tampa
- 专利权人: University of South Florida
- 当前专利权人: University of South Florida
- 当前专利权人地址: US FL Tampa
- 代理机构: Saliwanchik, Lloyd & Saliwanchik
- 主分类号: A61K35/26
- IPC分类号: A61K35/26 ; A01N25/00
摘要:
There is provided an isolated pluri-differentiated human mesenchymal progenitor cells (MPCs), a method for isolating and purifying human mesenchymal progenitor cells from Dexter-type cultures, and characterization of and uses, particularly therapeutic uses for such cells. Specifically, there is provided isolated MPCs which can be used for diagnostic purposes, to enhance the engraftment of hematopoietic progenitor cells, enhance bone marrow transplantation, or aid in the treatment or prevention of graft versus host disease.
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