Invention Grant
- Patent Title: 2-thioethenyl substituted carbapenem derivatives
- Patent Title (中): 2-硫代乙烯基取代的碳青霉烯衍生物
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Application No.: US11401892Application Date: 2006-04-12
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Publication No.: US07687490B2Publication Date: 2010-03-30
- Inventor: Takahisa Maruyama , Yuko Kano , Takashi Ando , Takehiko Sawabe , Nobuyoshi Baba , Hiromi Takata , Hisashi Suzuki , Kazuhiro Aihara , Toshiki Fujita
- Applicant: Takahisa Maruyama , Yuko Kano , Takashi Ando , Takehiko Sawabe , Nobuyoshi Baba , Hiromi Takata , Hisashi Suzuki , Kazuhiro Aihara , Toshiki Fujita
- Applicant Address: JP Tokyo
- Assignee: Meiji Seika Kaisha, Ltd.
- Current Assignee: Meiji Seika Kaisha, Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2005-114690 20050412; JP2005-235590 20050816
- Main IPC: C07D477/20
- IPC: C07D477/20 ; A61K31/426 ; A61K31/454 ; A61P31/04 ; C07D277/56 ; C07D277/26 ; C07D277/30 ; C07D277/40 ; C07D417/06
Abstract:
An objective of the present invention is to provide compounds that are effective against various resistant bacteria which cause current clinical problems, for example, pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including bata-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis.The present invention provides 2-ethenylthio-based carbapenem derivatives represented by the formula (I) or pharmaceutically acceptable salts thereof that are effective, for example, against pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis:
Public/Granted literature
- US20070004700A1 2-Thioethenyl substituted carbapenem derivatives Public/Granted day:2007-01-04
Information query
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