发明授权
US07589192B2 pH dependent ion exchange material capable of selectively binding to nucleic acids in comparison with proteins, solid substrate having the material immobilized on its surface, and method of isolating a nucleic acid using the material or the solid substrate
有权
与蛋白质相比能够选择性地结合核酸的pH依赖性离子交换材料，具有固定在其表面上的材料的固体底物，以及使用该材料或固体基质分离核酸的方法
- 专利标题： pH dependent ion exchange material capable of selectively binding to nucleic acids in comparison with proteins, solid substrate having the material immobilized on its surface, and method of isolating a nucleic acid using the material or the solid substrate
- 专利标题（中）： 与蛋白质相比能够选择性地结合核酸的pH依赖性离子交换材料，具有固定在其表面上的材料的固体底物，以及使用该材料或固体基质分离核酸的方法
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申请号： US11437210申请日： 2006-05-19
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公开(公告)号： US07589192B2公开(公告)日： 2009-09-15
- 发明人: Kyu-youn Hwang , Chang-eun Yoo
- 申请人： Kyu-youn Hwang , Chang-eun Yoo
- 申请人地址： KR
- 专利权人： Samsung Electronics Co., Ltd.
- 当前专利权人： Samsung Electronics Co., Ltd.
- 当前专利权人地址： KR
- 代理机构： Cantor Colburn LLP
- 优先权： KR10-2005-0042781 20050521
- 主分类号： C07H21/00
- IPC分类号： C07H21/00
摘要：
Provided is a pH dependent ion exchange material. The pH dependent ion exchange material has at least one monomer selected from the group consisting of M0, M1, M2 and M3 represented by the following formulae, provided that at least one monomer having A and at least one monomer having B are contained therein, the pH dependent ion exchange material having a degree of polymerization of 2-30,000. wherein A is a group —X(CH2)nY, wherein n is an integer from 1 to 10, X is a functional group which can react with an activated ester, and Y is a primary, secondary, tertiary amine or a nitrogen-containing aromatic heterocyclic base, B is a group —X′(CH2)nY′, wherein n is an integer from 1 to 10, X′ is a functional group which can react with an activated ester, and Y′ is an acid generating group having a pKa value of 4 or less, and R3 is an alkyl group having 1 to 10 carbon atoms.
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