发明授权
- 专利标题： 2-amino- and 2-thio- substituted 1,3-diaminopropanes
- 专利标题（中）： 2-氨基和2-硫代取代的1,3-二氨基丙烷
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申请号： US11090520申请日： 2005-03-25
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公开(公告)号： US07544717B2公开(公告)日： 2009-06-09
- 发明人: Roy Hom , John Tucker , Varghese John , Neerav Shah
- 申请人： Roy Hom , John Tucker , Varghese John , Neerav Shah
- 申请人地址： US CA South San Francisco
- 专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： A61K31/165
- IPC分类号： A61K31/165 ; A61K31/18 ; C07C233/36 ; C07C311/05
摘要：
Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.
公开/授权文献
- US20050267199A1 2-Amino- and 2-thio- substituted 1,3-diaminopropanes 公开/授权日：2005-12-01
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