发明授权
- 专利标题： Radiofluorination methods
- 专利标题（中）： 放射性氟化方法
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申请号： US10508682申请日： 2003-03-20
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公开(公告)号： US07368474B2公开(公告)日： 2008-05-06
- 发明人: Alan Cuthbertson , Magne Solbakken , Joseph Maduabuchi Arukwe , Hege Karlsen
- 申请人： Alan Cuthbertson , Magne Solbakken , Joseph Maduabuchi Arukwe , Hege Karlsen
- 申请人地址： GB Buckinghamshire
- 专利权人： GE Healthcare Limited
- 当前专利权人： GE Healthcare Limited
- 当前专利权人地址： GB Buckinghamshire
- 优先权： GB0206750.2 20020322
- 国际申请： PCT/GB03/01332 WO 20030320
- 国际公布： WO03/080544 WO 20031002
- 主分类号： A61K51/08
- IPC分类号： A61K51/08 ; A61K101/02
摘要：
The present invention relates to methods and reagents for [18F]-fluorination, particularly of peptides. The resultant 18F-labelled compounds are useful as radiopharmaceuticals, specifically for use in Positron Emission Tomography (PET). Thus, a compound of formula 18F-(Linker)-SH, such as a compound of formula (IV), (V), or (VI): 18F—(CH2CH2O)n—(CH2)m—SH (IV) 18F—(CH2)p—SH (V) may be reacted with an activated peptide as a means for 18F-labelling.
公开/授权文献
- US20050142061A1 Radiofluorination methods 公开/授权日：2005-06-30
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